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Shrinks fat cells in mice In diet-induced obese mice, 11 days of 5-Amino-1MQ (subcutaneous, around 34 mg/kg/day) reduced body weight, total fat mass, and plasma cholesterol with no drop in food intake or lean mass

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The combined actions of immune cell infiltration, pathological angiogenesis, and extracellular matrix remodeling shape the characteristic multi-zonal architecture of tophi and define their progressive nature

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